CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in medical and biomedical sciences.
Edited by: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP)
CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in medical and biomedical sciences.
Edited by: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP)
16/Aug/2021
Daniele Moraes Losada , André Luiz da Cruz Ribeiro , Francisco Fontes Cintra , Guilherme Rossi Assis de Mendonça , Maurício Etchebehere , Eliane Maria Ingrid Amstalden
DOI: 10.6061/clinics/2021/e2914
OBJECTIVES: The aim of this study was to evaluate the role of amphiregulin protein, an epidermal growth factor receptor ligand, in cartilaginous tumors. METHODS: Amphiregulin expression was examined in 31 enchondromas and 67 chondrosarcomas using immunohistochemistry analysis. RESULTS: Overall, 15 enchondromas (48.40%) and 24 chondrosarcomas (35.82%) were positive for amphiregulin. According to the receiver operating characteristic curve test, no difference in amphiregulin expression was observed between enchondromas and low-grade chondrosarcomas (p=0.0880). Additionally, 39 lesions Enchondromas or chondrosarcomas? Please clarify. This […]
Keywords: Amphiregulin; Bone Tumors; Chondrosarcoma; Enchondroma; Immunohistochemistry