Clinics (Sao Paulo). 2020;75:e2181.
The influence of bitter-taste receptor (TAS2R) expression in pharmacological response to Chloroquine in obese patients with COVID-19
Lígia Moriguchi Watanabe
, Izabella Ferreira Pires, Natália Yumi Noronha
, Marcela Augusta de Souza Pinhel
, Carla Barbosa Nonino
DOI: 10.6061/clinics/2020/e2181
CONCLUSION
The COVID-19 pandemic is a significant global public health challenge, especially concerning the pursuit of effective drugs for its prevention and treatment. Considering the prevalence of obesity worldwide and the complications associated with excessive body mass ratio, special attention should be given to patients with obesity. In a condition of obesity, reduced TAS2R expression could affect the response to medications such as CQ. Altogether, we highlighted the importance of obese patient care, particularly during the current COVID-19 pandemic.
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