Clinics (Sao Paulo). 2020;75:e2407.
Neonatal manifestations in COVID-19 patients at a Brazilian tertiary center
Glenda Priscila Neves dos Santos Beozzo
, Werther Brunow de Carvalho
, Vera Lucia Jornada Krebs
, Maria Augusta Bento Cicaroni Gibelli
, Romy Schmidt Brock Zacharias
, Larissa Elizabeth Schulz Rossetto
, Rossana Pulcinelli Vieira Francisco
DOI: 10.6061/clinics/2020/e2407
The most common symptoms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children are fever and cough, which are present in approximately 59% of cases (). Other symptoms include bloating, nausea, vomiting, diarrhea, and abdominal pain. Although the evolution is generally benign, the clinical picture of SARS-CoV-2 infection in neonates is still poorly understood (). It is always necessary to consider that severe respiratory distress can also occur in other conditions that are inherent to pulmonary immaturity at this stage of life. Although most newborns are able to make a full recovery from SARS-CoV-2 infection, there have been reports of sepsis, severe respiratory failure, and shock (,).
A total of 49 newborns were born to mothers with proven SARS-CoV-2 infection between April and June 2020 in a Brazilian tertiary center. These neonates received a SARS-CoV-2 test by reverse transcriptase polymerase chain reaction (RT-PCR) using nasal and oropharynx secretions. As a result, two newborns tested positive 48 hours after birth and two positive newborns were admitted to the Unit as out-born cases, one of whose case has already been reported in a previous study ().
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