CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in medical and biomedical sciences.
Edited by: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP)
CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in medical and biomedical sciences.
Edited by: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP)
01/Apr/2008
Siti Fatimah Ibrahim, Khairul Osman, Srijit Das, Abas Mazni Othman, Norzaiti Abdul Majid, Mohd Padzil Abdul Rahman
DOI: 10.1590/S1807-59322008000400022
OBJECTIVE: Assisted reproductive techniques are useful in helping infertile couples achieve successful conception. Initial studies have shown that sperm cryopreservation, one step in assisted reproduction, causes a dramatic reduction in sperm quality. This has been attributed to, among other things, free radical activities. The aim of the present study was to minimize this oxidative attack by adding an antioxidant into the sperm microenvironment. Alpha lipoic acids were selected for this purpose for their efficient free radical scavenging properties and solubility […]
Keywords: Action; Alpha lipoic acids; Analysis; Antioxidant; Oxidative Stress; Semen; Sperm
01/Apr/2007
Wellington Andraus, José Jukemura, Fernando Dutra, Etelvino Bechara, José E. M. Cunha, Marcel Cerqueira César Machado
DOI: 10.1590/S1807-59322007000400016
BACKGROUND: Hypothermia is a frequent event in severe acute pancreatitis (AP) and its real effects on the normal pancreas have not been well demonstrated. Moreover, neither have its effects on the outcome of acute pancreatitis been fully investigated. One hypothesis is that oxidative stress may be implicated in lesions caused or treated by hypothermia. AIM OF THE STUDY: To investigate the effect of hypothermia in cerulein-induced acute pancreatitis (CIAP) in rats and the role played by oxidative stress in this […]
Keywords: Acute Pancreatitis; Cerulein; Glutathione; Hypothermia; Oxidative Stress